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机器学习研究员,基因组人工智能(驻地,美国)

雇主

Bayer

地点

远程 · Remote · 美国

待遇

$USD 110,000 - USD 150,000 / annual

工作模式

远程

截止日期

1月5日

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岗位摘要

At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where 'Health for all Hunger for none’ is no longer a dream, but a real possibility.

岗位职责

At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where 'Health for all Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us. If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice.
Machine Learning Researcher, Genomic AI
We are seeking a Machine Learning Researcher with expertise in machine learning for biological systems, particularly genomic and multi-omic data modeling. This role is centered on building and deploying state-of-the-art AI models - including large-scale genomic language models and deep representation learning architectures - that extract actionable biological insight from complex molecular datasets. You will develop models that learn the grammar of genomes, predict functional consequences of genetic variation, and connect molecular signatures to whole-organism phenotypes across diverse crop species. This work directly supports genomic selection and genome editing target identification, turning sequence-level intelligence into breeding and discovery decisions at a global scale.
YOUR TASKS AND RESPONSIBILITIES
The primary responsibilities of this role are:
Genomic & Omic Model Development: Design, train, and evaluate deep learning models (LLMs, transformers, and representation learning architectures) on whole-genome sequences, gene expression profiles, epigenomic marks, k-mer spectra, skim-seq, pangenome graphs, and multi-omic integrations.
Genomic Language Models:Develop and fine-tune foundation models for DNA/RNA sequences that capture long-range dependencies and regulatory grammar to predict variant effects, gene function, and trait associations in crop genomes.
Genomic Selection & Editing Enablement: Build predictive models connecting genotype to phenotype across environments, identify high-value editing targets, and rank candidate genetic interventions with biological interpretability and statistical rigor.
Functional Data Integration:Integrate heterogeneous biological data types with high-resolution genome assemblies, structural variants, gene regulatory networks, protein structure predictions, and phenomic measurements-into unified predictive frameworks.
Interdisciplinary Collaboration:Work closely with molecular biologists, geneticists, breeders, bioinformaticians, and computational scientists to ground models in biological reality, design informative training data strategies, and validate predictions experimentally.
Scalable Deployment:Partner with engineering and IT teams to operationalize models within genomic selection pipelines, editing nomination workflows, and decision-support platforms used by breeding programs globally.
Documentation & Communication: Communicate complex modeling results to diverse audiences, prepare technical reports, and build organizational confidence in AI-driven biological discovery.
WHO YOU ARE
Bayer seeks an incumbent who possesses the following:
Required:
PhD in Computational Biology / Bioinformatics, Genomics / Statistical Genetics, Machine Learning / Deep Learning, Computer Science (with focus on biological or sequential data), Biostatistics / Quantitative Genetics, Systems Biology, or a closely related quantitative discipline with demonstrated application to biological data.
Demonstrated research experience building and training deep learning models on biological sequence data or high-dimensional omic datasets.
Proficiency in modern deep learning frameworks (PyTorch, JAX, or TensorFlow) and familiarity with large-scale model training (distributed training, GPU clusters).
Working knowledge of molecular biology fundamentals sufficient to interpret model outputs in biological context (e.g., gene regulation, variant consequence, population genetics).
Strong written/verbal communication and cross-disciplinary collaboration skills.
Preferred:
Hands-on experience developing or fine-tuning genomic language models or biological foundation models (e.g., GPN, PlantCaduceus, Nucleotide Transformer, Evo, Enformer, AlphaGenome or similar large-scale sequence architectures for genomic prediction and functional track prediction).
Experience with functional genomics data: ATAC-seq, ChIP-seq, Hi-C, single-cell transcriptomics, or CRISPR screen data.
Background in quantitative genetics or genomic prediction (e.g., GBLUP, Bayesian alphabet models, marker-effect estimation) and understanding of breeding program workflows.
Familiarity with multi-omic data integration methods (e.g., multi-modal autoencoders, contrastive learning across modalities, graph neural networks on biological networks).
Knowledge of pangenomics, structural variant calling, or comparative genomics across crop species.
Experience with self-supervised, semi-supervised, or transfer learning strategies for data-efficient modeling in biology.
Familiarity with interpretability/explainability methods (attention visualization, in-silico mutagenesis, feature attribution) to derive biological hypotheses from model internals.
Exposure to classical ML approaches (gradient-boosted methods, kernel methods, Gaussian processes) as complementary or baseline tools.
Experience with model deployment in production (MLOps pipelines, containerization, API development, cloud/HPC infrastructure).
Track record of interdisciplinary collaboration with experimental biologists, resulting in validated biological predictions.
Employees can expect to be paid a salary of approximately $110k-150k. Additional compensation may include a bonus or incentive program (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc.. This salary (or salary range) is merely an estimate and may vary based on an applicant’s location, market data/ranges, an applicant’s skills and prior relevant experience, certain degrees and certifications, and other relevant factors.
This posting will be available for application until at least 10/16/26.
YOUR APPLICATIONBayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Health for all, Hunger for none, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer.
To all recruitment agencies: Bayer does not accept unsolicited third party resumes.
Bayer is an Equal Opportunity Employer/Disabled/Veterans
Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.
Equal Opportunity Employer Statement:Notice for U.S. Visitors: All information on this site is subject to compliance with local rule and regulations as they may vary from time to time and across different geographies, including, without limitation, U.S. Executive Orders.Bayer is an E-Verify Employer.
Location:United States : Residence Based : Residence Based || United States : Missouri : Creve Coeur Division:Crop Science Reference Code:872400 Contact UsEmail: Originally posted on Himalayas

申请条件

- 具备机器学习研究经验,专长于生物系统建模,尤其是基因组和多组学数据建模
- 能够设计、训练和评估深度学习模型(包括大语言模型、Transformer和表征学习架构)
- 熟悉全基因组序列、基因表达谱、表观基因组标记、k-mer频谱、skim-seq、泛基因组图和多组学整合数据
- 具备开发和微调DNA/RNA序列基础模型的能力,能够捕捉长程依赖和调控语法
- 能够预测变异效应、基因功能和性状关联
- 能够从复杂分子数据集中提取可操作的生物学见解
- 能够将分子特征与跨作物物种的全生物体表型联系起来
- 支持基因组选择和基因组编辑靶点识别
- 能够将序列层面的智能转化为育种和发现决策

雇主简介

Bayer is a global enterprise with core competencies in the life science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life.

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数据来源:Himalayas

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