博士：欧盟实验室安全病毒研究的实施策略

MERIT (MEtabolic Reprogramming in viral pathogenesis: from Infection to Therapeutic innovations) is an EU-funded

MSCA training programme aimed at better understanding how viruses affect the human body.

Coordinated by Dr. Adithya Sridhar, Assistant Professor, and Prof. Dr. Dasja Pajkrt, Professor of Pediatric Infectious diseases, from the OrganoVIR Labs at Amsterdam UMC (location AMC), this project brings together 7 academic institutions and 12 associated partners from across Europe.

Within MERIT, researchers will take a new, holistic approach that focuses on infections and host metabolism to unravel virus-induced metabolic reprogramming and its impact on human health.

The project’s objective lies in understanding the complex interplay between viruses and host cells, focusing on metabolic reprogramming, and long-term consequences of infection.

This will be achieved by combining three methodological pillars: human organoids, integrative and spatial omics, and advanced microscopy.

About the role The project aims to bridge the gap between biosafety guidelines and everyday laboratory practice by strengthening the implementation of safety measures.

Using an implementation science approach, the project will systematically identify behavioural, social, and organisational determinants of compliance, and translate these into tailored, context-sensitive implementation strategies.

Through qualitative and mixed methods research (e.g. literature reviews, interviews, questionnaires including discrete choice experiments or vignettes, and observations) the project will map the key drivers and barriers of safety behaviour.

Building on these insights, it will explore how these determinants shape the mechanisms through which implementation strategies work, and under which conditions they are most effective and sustainable.

In close collaboration with laboratory staff, including doctoral candidates and supervisors, suitable implementation strategies will be selected and tailored to local workflows, resources, and safety culture, and subsequently piloted in real-world laboratory settings.

Ultimately, the project aims to enhance biosafety, research quality, and public trust in high-risk pathogen research.

MERIT is looking for a Doctoral Candidate (DC) to work on Work Package 2. As DC2, your objectives are: • to identify behavioural, social, and organisational determinants of compliance with safety measures through literature review, interviews, questionnaires (discrete choice models or vignettes), and observations;

• to explore how these determinants influence mechanisms through which implementation strategies work;

• to work together with laboratory staff, DCs and supervisors to select and tailor implementation strategies;

• to pilot and evaluate these strategies in real-world laboratory settings across multiple EU institutions, focusing on their feasibility, acceptability, and appropriateness and their potential to strengthen compliance with biosafety practice.

You will be guided during your research project by Dr. Rosa van Mansfeld, Dr. Mireille Dekker and Dr. Adithya Sridhar.

You can apply for this position until 30 October 2026. Applications submitted after this date will not be considered.

• have not resided/carried out work or studies in the Netherlands for more than 12 months in the 36 months immediately before 1 April 2027 (transnational mobility rule).

Our offer • A contract with Amsterdam UMC for 36 hours per week for 4 years (probation of 6 months).

• The opportunity to work with motivated colleagues from all over the world.

• Planned secondments in Poland (JU), Innsbruck (MUI) and Sweden (KI).

• Training in safety and biosecurity aligned with international best practices.

You will be trained in hazard identification, containment, incident reporting, and dual-use/gain-of-function issues.

• An opportunity to take part in a tailor-made pre-MBA programme to develop entrepreneurial and commercial skills and other network-wide training opportunities including conferences and courses, a Personal Development Plan, non-academic coaching, and workshops on topics including ethics and sustainability and

AI/LLM.

• Classification in salary scale OIO: € 3,217 to € 4,077 gross for full-time employment (depending on experience).

In addition to a good basic salary, we offer 8.3% end-of-year bonus.

Calculate your net salary here.

• 100% reimbursement for public transport travel costs and, for private transport, €0.18 per km up to a maximum of 40 km each.

Take advantage of our good bike scheme.

About the workplace Amsterdam UMC, location AMC, houses the university hospital and the medical faculty of the University of Amsterdam, as well as several research institutes.

The research group Implementation of Infection Prevention (IIP) is embedded within the Department of Medical Microbiology and Infection Prevention (MMI) and is affiliated with OrganoVIR Labs.

The research group IIP collaborates with the Amsterdam Immunity and Infection Institute,the Amsterdam Public Health research institute, and other (inter)national researchers.

From various perspectives, we focus on improving infection prevention in healthcare.

Our scientific research integrates knowledge and insights from fields such as implementation science and behavioural science.

The OrganoVIR Labs is uniquely embedded within both the Department of Medical Microbiology and Infection Prevention (MMI) and the Department of Pediatrics and is affiliated with the Amsterdam Immunity and Infection Institute (AIII), Amsterdam Reproduction and Development (AR&D), and Emma Centre for Personalized Medicine (Emma CPM).

This multidisciplinary positioning fosters close collaboration between fundamental, translational, and clinical research.

Master's degree in biomedical sciences, health sciences, or related fields.

Demonstrable affinity with qualitative and quantitative research and data analysis.

Excellent oral and written communication skills in English (minimum C1/C2 CEFR level).